Acute Traumatic Intervertebral Disc Herniation

Intervertebral disc herniation in adolescents.

BACKGROUND The purpose of this study was to review surgery-proven lumbar disc herniation in adolescents with an emphasis on the distinguishing features. METHODS Twenty-eight adolescents between 14 and 18 years old had lumbar discectomy after conservative treatment for 9 months. Indications for surgery were intractable pain and failure of conservative treatment for more than 6 weeks. Lumbar sp...

Intervertebral Disc Herniation: Pathophysiology and Emerging Therapies

Approximately 2.6 % of the US population visits a physician for treatment of spinal disorders annually (Fraser 2009 ) with costs of $7.1 billion from lost work days alone (Ricci et al. 2006 ) . “Herniation” of the intervertebral disc is one of the several spinal disorders that contribute to this very high incidence, with potential to cause signi fi cant pain, neurological de fi cit, and functio...

Tophaceous Gout of the Cervical Spine Mimicking Intervertebral Disc Herniation

Tophaceous gout involving the intervertebral disc is rare and may present with neurologic symptoms secondary to spinal cord or nerve root compression. We report a case of a 50-year-old male with a history of hyperuricemic gout who received intermittent medical treatment and had a history of alcoholism. Quadriparesis developed over a period of one month. Magnetic resonance imaging of the cervica...

Intervertebral disc herniation, spinal nociceptive signaling and pro- inflammatory mediators

Natural history of extruded lumbar intervertebral disc herniation.

We studied the natural history of extruded lumbar intervertebral discs using MRI. Forty-nine patients with lumbar disc herniation were included in this study. Ages ranged from 19 to 57. On the T2-weighted sagittal MR image, the signal intensity in the herniated mass was measured and the ratio to that in the original nucleus (i.e., nucleus pulposus from which they extruded) was calculated (signa...